The Dynamin-2 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to DNM2, DYN2, Dynamin 2, and Udnm. This antibody recognizes Human antigen. The Dynamin-2 Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Background: Dynamin-2 (Dyn2), with 870-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin 1 is expressed exclusively in neurons, Dynamin 2 is ubiquitously expressed and Dynamin 3 is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis